Table 3.
Compd | n | R2 | R1 | pIC50 ± SE | IC50 (μM) |
---|---|---|---|---|---|
62 | 1 | 3,4-Dimethyl | Furfuryl | 2.32 ± 0.48 | >1000 |
63 | 2 | 3,4-Dimethyl | Furfuryl | 2.95 ± 0.26 | >1000 |
64 | 1 | 4-iPr | Furfuryl | 4.40 ± 0.03 | 40 |
65 | 1 | 4-iPr | Allyl | 3.86 ± 0.11 | 138 |
66 | 1 | 4-iPr | 3-OMe-propyl | 3.79 ± 0.14 | 164 |