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. 2014 Sep 30;9(9):e108183. doi: 10.1371/journal.pone.0108183

Table 3. Baseline leukocyte subsets and plasma cytokines of patients and controls.

SA NSTE-ACS Controls P-value
N = 30 N = 20 N = 37
Leukocytes (x109/L) 7.1±2.2 7.7±2.3 5.5±1.4 <0.001ψγ
Neutrophils (x109/L) 4.1±1.5 4.5±1.7 3.0±1.0 <0.001ψγ
Monocytes (x109/L) 0.6±0.2 0.6±0.3 0.4±0.1 <0.001ψγ
Lymphocytes (x109/L) 2.2±1.0 2.4±0.9 2.0±0.6 NS
CD19+ cells, % of lymphocytes 10 (7,12) 10 (8,15) 10 (7,14) NS
CD4+ cells, % of lymphocytes 49 (42,54) 50 (44,54) 39 (33,48) 0.005ψ, 0.001γ
CD8+ cells, % of lymphocytes 25 (20,31) 25 (17,31) 23 (19,29) NS
NK cells, % of lymphocytes 12 (9,18) 12 (7,15) 18 (11,28) 0.023ψγ
Neutrophil/lymphocyte ratio 2.1 (1.4,2.4) 2.0 (1.5,2.5) 1.5 (1.2,1.9) 0.012ψ, 0.027γ
Plasma IL-6, pg/mL 3.1 (2.0,5.7) 4.9 (2.9,8.0) 1.4 (1.0,2.2) <0.001ψγ
Plasma CRP, mg/L 1.2 (0.3,3.2) 3.2 (2.2,5.0) 0.7 (0.4,1.2) 0.023Φ, <0.001γ

The data are presented as mean ±SD or median (25th, 75th percentile). SA =  stable angina; NSTE-ACS =  non-ST-elevation acute coronary syndrome; CD19+ cells, B cells; CD4+ cells, T helper cells; CD8+ cell, cytotoxic T cell; NK =  Natural killer; IL =  interleukin; CRP =  C-reactive protein. NS =  non-significant (p≥0.05). For comparisons between groups, p-values indicating significant differences are denoted by ψ (controls vs SA), γ (controls vs NSTE-ACS) and Φ (SA vs NSTE-ACS), respectively.