Figure 2. Increase in HIV entry requires a minimum threshold of dopamine.
MOI 0.01 β-lac HIV was added to macrophages in the presence of 1010, 109, 2×109, 5×109, 108, 107, 106 M and 105 M dopamine and control cells were infected with HIV alone. Relative to control infections, viral entry was significantly increased when MDM were infected with HIV in the presence of 108, 107, 106 M and 105 M dopamine (n = 1032, ** p < 0.01, *** p < 0.001 vs. HIV only) but not in the presence of 1010, 109, 2×109, or 5×109 M dopamine. There was no significant difference in the magnitude of the increase in entry among cultures infected the presence of 108, 107, 106 M and 105 M dopamine.