Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 30;9(9):e108559. doi: 10.1371/journal.pone.0108559

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Xie et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Arrows show senescent neurons (A, inset windows) and cell disorder arrangement (A) in the DM group compared to the healthier hippocampal neurones in the DM + shRNA group and the normal ones in the con group. Immunohistochemistry of hippocampus tissue indicated the place and expression levels of Grb10 Interacting GYF Protein 2 (GIGYF2). Integrated optical density (IOD) values were measured by Image-Pro Plus, version 6.0, and expressed as the mean ± SEM (n = 3) of two independent experiments. (*p<0.05 vs con; ^# p<0.05 vs DM + shRNA) Abbreviations: con: normal control group; DM: diabetes mellitus group; DM +0: diabetes mellitus sham-knocked down group; DM + shRNA: diabetes mellitus GIGYF2-knockdown group.