. 2014 Sep 30;9(9):e108511. doi: 10.1371/journal.pone.0108511

Table 2. Expression of genes involved in cell cycle in LS-174T i.p. xenografts following treatment with Paclitaxel and ²¹²Pb-trastuzumab.

Symbol	Gene name	GeneBank ID	Fold change
			Paclitaxel-²¹²Pb-trastuzumab	p	Paclitaxel-²¹²Pb-HuIgG	p	Paclitaxel	p
BRCA1	Breast Cancer 1, early onset	NM_007294	−3.8	0.0005	−3.0	0.0022	−2.1	0.0061
CHK1	CHK1 checkpoint homolog	NM_001274	−4.0	0.0001	−3.2	0.0002	−2.4	0.0018
CHK2	CHK2 checkpoint homolog	NM_007194	−2.0	0.0016	−1.9	0.0025	−2.4	0.0032
GADD45α	Growth arrest and DNA-damage-inducible, alpha	NM_001924	5.9	0.0001	3.8	0.0002	1.9	0.0962
GML	Glycosylphosphatidylinositol anchored molecule like protein	NM_002066	26.4	0.0004	2.7	0.0023	−1.4	0.4430
GTSE1	G-2 and S-phase expressed 1	NM_016426	−9.3	0.0014	−4.3	0.0025	−3.1	0.0043
NBN	Nibrin	NM_002485	−2.0	0.0303	−2.1	0.0065	−1.4	0.0999
PCBP4	Poly(rC)binding protein 2	NM_020418	3.1	0.0116	2.8	0.0012	1.6	0.0205
PPP1R15A	Protein phosphatase 1, regulatory subunit 15A	NM_014330	2.6	0.0115	1.4	0.0399	−1.1	0.4490
RAD9A	RAD9 homolog A	NM_004584	2.4	0.0016	1.6	0.0006	−1.3	0.0132
SESN1	Sestrin1	NM_014454	4.6	0.0001	3.8	0.0006	2.8	0.0004

Table 2. Expression of genes involved in cell cycle in LS-174T i.p. xenografts following treatment with Paclitaxel and 212Pb-trastuzumab.