Table 3. Expression of gene expression involved in DNA repair in LS-174T i.p. xenografts following treatment with Paclitaxel and ²¹²Pb-trastuzumab.

Symbol	Gene name	GeneBank ID	Fold change
			Paclitaxel-212Pb-trastuzumab	p	Paclitaxel-212Pb-HuIgG	p	Paclitaxel	p
ATRX	Alpha thalassemia/mental retardation	NM_000489	2.8	0.0018	1.4	0.1413	1.1	0.4611
BRCA1	Breast Cancer 1, early onset	NM_007294	−3.8	0.0005	−3.0	0.0022	−2.1	0.0061
BTG2	BTG family, member 2	NM_006763	7.5	0.0006	5.4	0.0003	2.7	0.0001
EXO1	Exonuclease 1	NM_130398	−4.5	0.0004	−4.0	0.0003	−2.1	0.0030
FEN1	Flap structure-specific endonuclease 1	NM_004111	−4.5	0.0024	−5.8	0.0017	−2.4	0.0072
IGHMBP2	Immunoglobulin mu binding protein 2	NM_002180	2.4	0.0013	1.8	0.0307	−1.4	0.0430
MSH2	MutS homolog 2	NM_000251	−2.9	0.0080	−2.7	0.0085	−1.9	0.0249
MUTYH	MutY homolog	NM_012222	2.8	0.0002	2.0	0.0019	−1.4	0.0837
NBN	Nibrin	NM_002485	−2.0	0.0303	−2.1	0.0065	−1.4	0.0999
OGG1	8-oxoguanine DNA glycosylase	NM_002542	−2.2	0.1217	−2.2	0.1214	−1.9	0.2046
PNKP	Polynucleotise kinase 3′-phosphatase	NM_007254	2.4	0.0063	2.1	0.0014	−1.5	0.0084
PPP1R15A	Protein phosphatase 1, regulatory unit 15A	NM_014330	2.6	0.0115	1.4	0.0399	−1.1	0.4490
PRKDC	Protein kinase, DNA-activated, catalytic polypeptide	NM_006904	−2.7	0.0187	−2.5	0.0126	−1.9	0.0306
RAD18	RAD18 homolog	NM_020165	−2.3	0.0030	−1.9	0.0003	−1.6	0.0001
RAD21	RAD21 homolog	NM_006265	−3.1	0.0001	−2.5	0.0002	−1.7	0.0184
SEMA4A	Semadomain, immunoglobulin domain, cycloplastic domain 4A	NM_022367	2.8	0.0350	2.7	0.0031	1.3	0.3131
p73	Tumor protein p73	NM_005427	2.7	0.0009	5.6	0.0021	2.9	0.0628
XPC	Xeroderma pigmentosum, complementation group C	NM_004628	5.1	0.0001	3.7	0.0001	1.9	0.0141
XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	NM_005431	−3.5	0.0020	−3.0	0.0003	−2.2	0.0025