Figure 1. Administration of selegiline (SEL) improves survival after polymicrobial sepsis.
A graph of the Kaplan-Meier survival of rats which received sham operation (SOP, n = 11), SOP and selegine administration (SOP + SEL, 3 mg/kg, i.v. at 3 h after SOP, n = 11), cecal ligation and puncture plus saline (CLP, n = 27) and CLP and SEL administration (CLP + SEL, 3 mg/kg, i.v. at 3 h after CLP, n = 23). The survival time was recorded for 18 hrs. *P<0.05, CLP vs. SOP; †P<0.05, with vs. without SEL in animals treated with CLP. Data are expressed as percentage of rats survived at the observed time point.