Figure 3. Cellular responses of the combinations rLdHSP70 + rLdPDI/rLdHSP70 + rLdTPI/rLdHSP70 + rLdEL-2 in patients sample.
(A) LTT response of PBMC from L. donovani infected, endemic and cured patients in response to PHA, SLD and recombinant test antigens individually and in combination with rLdHSP70 10 µg/ml each. Proliferation was represented as mean O.D of stimulated cell - mean O.D of unstimulated control. Each bar represents the pooled data (mean ± S.D. value) of stimulated PBMCs of each group. (B) Significance values indicate the difference between the SLD and rLdHSP-70/rLdPDI/rLdTPI/rLdEL-2 and rLdHSP-70 + rLdPDI/rLdHSP-70 + rLdTPI/rLdHSP-70 + rLdEL-2 stimulation (*, p<0.05**, p<0.01; ***, p<0.001).