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. 2014 Sep 30;9(9):e108556. doi: 10.1371/journal.pone.0108556

Figure 3. Cellular responses of the combinations rLdHSP70 + rLdPDI/rLdHSP70 + rLdTPI/rLdHSP70 + rLdEL-2 in patients sample.

Figure 3

(A) LTT response of PBMC from L. donovani infected, endemic and cured patients in response to PHA, SLD and recombinant test antigens individually and in combination with rLdHSP70 10 µg/ml each. Proliferation was represented as mean O.D of stimulated cell - mean O.D of unstimulated control. Each bar represents the pooled data (mean ± S.D. value) of stimulated PBMCs of each group. (B) Significance values indicate the difference between the SLD and rLdHSP-70/rLdPDI/rLdTPI/rLdEL-2 and rLdHSP-70 + rLdPDI/rLdHSP-70 + rLdTPI/rLdHSP-70 + rLdEL-2 stimulation (*, p<0.05**, p<0.01; ***, p<0.001).