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. 2014 Jun 10;13(4):203–215. doi: 10.1007/s12522-014-0184-2

Figure 3.

Figure 3

PSCs from various developmental stages of mice, rabbits and humans. There are two major types of PSCs—the naive state which are dependent on LIF and have compact colonies and the primed state which are dependent on FGF and activin and have flat colonies. Naive PSCs are able to be dissociated and passaged as single cells, while primed PSCs are passaged as a small clump of cells or with ROCK inhibitors