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IC50 values of vemurafenib, perifosine, regorafenib, and trametinib (BrdU incorporation assay).
| Vemurafenib (µM) | Perifosine (µM) | Regorafenib (µM) | Trametinib (nM) | |
|---|---|---|---|---|
| HROC18 | 8.3 | 15.4 | 1.3 | 39.9 |
| HROC24 | 0.8 | 6.7 | 4.6 | 5.1 |
| HROC43 | 9.9 | 8.7 | 5.3 | 89.2 |
| HROC46 | 12.7 | # | 2.4 | 252 |
#: no inhibitory effects on BrdU incorporation under experimental conditions.
