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. 2014 Oct 1;9(10):e108398. doi: 10.1371/journal.pone.0108398

Table 2. Demographics, clinical characteristics and source of Infection of 71 patients at the time of diagnosis.

PersistentPIGN (n = 42) HealedPIGN (n = 28) P-value
Sex
Male (%) 27 (64) 17 (61) 0.8
Female (%) 15 (36) 11 (39)
Age (median, IQR) 45 (41, 52) 48.5 (42, 54.5) 0.47
Race - no. of patients (%)
Black 38 (91) 24 (86) 0.41
White 2 (5) 4 (14)
Asian 1 (2) 0 (0.00)
Others 1 (2) 0 (0.00)
Serum creatinine (Median, IQR) 2.2 (1.1, 4.9) 2.6 (1.9, 5.1) 0.31
CD4 count (Median, IQR) 327 (199, 506) 238 (77, 459) 0.26
Comorbidities - no. of patients (%)
Diabetes 11 (28) 6 (23) 0.8
Hypertension 35 (88) 22 (79) 0.34
Hepatitis C 24 (63) 14 (56) 0.61
Cirrhosis 1 (3) 2 (7) 0.57
Malignancy 8 (21) 3 (11) 0.34
Other systemic diseases 5 (13) 5 (20) 0.5
Intravenous drug use 19 (50) 10 (42) 0.61
Low C3 8 (25) 2 (10) 0.28
Low C4 8 (25) 2 (10) 0.28
Site of Infection –no. of patients (%)
Endocardium 12 (29) 4 (14) 0.59
Bone/Joint 1 (2) 2 (7)
Pleura 1 (2) 0 (0)
Skin 4 (10) 4 (14)
Lung/URTI 6 (14) 5 (18)
Others 2 (5) 0 (0.00)
None identified 16 (38) 14 (50)
Infectious Agent – no. of patients (%) N = 26 N = 25
Staphylococcus 11 (42) 14 (56) 0.31
Streptococcus 7 (27) 8 (32)
Others 8 (31) 3 (12)
HIV medications – no. of patients (%)
NRTI 21 (66) 11 (78) 0.5
NNRTI 7 (22) 2 (14) 0.7
PI 19 (59) 8 (57) 1
Other medications – no. of patients (%)
ACE Inhibitors 19 (50) 12 (46) 0.8
ARB 1 (3) 1 (4) 1
Corticosteroid 9 (23) 3 (11) 0.51
Antibiotic use 24 (62) 16 (62) 0.92
Nephrotic Proteinuria 8 (26) 11 (46) 0.16
Hematuria 23 (62) 8 (30) 0.02