Table 2. Demographics, clinical characteristics and source of Infection of 71 patients at the time of diagnosis.
PersistentPIGN (n = 42) | HealedPIGN (n = 28) | P-value | |
Sex | |||
Male (%) | 27 (64) | 17 (61) | 0.8 |
Female (%) | 15 (36) | 11 (39) | |
Age (median, IQR) | 45 (41, 52) | 48.5 (42, 54.5) | 0.47 |
Race - no. of patients (%) | |||
Black | 38 (91) | 24 (86) | 0.41 |
White | 2 (5) | 4 (14) | |
Asian | 1 (2) | 0 (0.00) | |
Others | 1 (2) | 0 (0.00) | |
Serum creatinine (Median, IQR) | 2.2 (1.1, 4.9) | 2.6 (1.9, 5.1) | 0.31 |
CD4 count (Median, IQR) | 327 (199, 506) | 238 (77, 459) | 0.26 |
Comorbidities - no. of patients (%) | |||
Diabetes | 11 (28) | 6 (23) | 0.8 |
Hypertension | 35 (88) | 22 (79) | 0.34 |
Hepatitis C | 24 (63) | 14 (56) | 0.61 |
Cirrhosis | 1 (3) | 2 (7) | 0.57 |
Malignancy | 8 (21) | 3 (11) | 0.34 |
Other systemic diseases | 5 (13) | 5 (20) | 0.5 |
Intravenous drug use | 19 (50) | 10 (42) | 0.61 |
Low C3 | 8 (25) | 2 (10) | 0.28 |
Low C4 | 8 (25) | 2 (10) | 0.28 |
Site of Infection –no. of patients (%) | |||
Endocardium | 12 (29) | 4 (14) | 0.59 |
Bone/Joint | 1 (2) | 2 (7) | |
Pleura | 1 (2) | 0 (0) | |
Skin | 4 (10) | 4 (14) | |
Lung/URTI | 6 (14) | 5 (18) | |
Others | 2 (5) | 0 (0.00) | |
None identified | 16 (38) | 14 (50) | |
Infectious Agent – no. of patients (%) | N = 26 | N = 25 | |
Staphylococcus | 11 (42) | 14 (56) | 0.31 |
Streptococcus | 7 (27) | 8 (32) | |
Others | 8 (31) | 3 (12) | |
HIV medications – no. of patients (%) | |||
NRTI | 21 (66) | 11 (78) | 0.5 |
NNRTI | 7 (22) | 2 (14) | 0.7 |
PI | 19 (59) | 8 (57) | 1 |
Other medications – no. of patients (%) | |||
ACE Inhibitors | 19 (50) | 12 (46) | 0.8 |
ARB | 1 (3) | 1 (4) | 1 |
Corticosteroid | 9 (23) | 3 (11) | 0.51 |
Antibiotic use | 24 (62) | 16 (62) | 0.92 |
Nephrotic Proteinuria | 8 (26) | 11 (46) | 0.16 |
Hematuria | 23 (62) | 8 (30) | 0.02 |