Table 3. Summary of pathological findings on 70 patients with persistent and healed PIGN.
Pathological Finding –no of patients (%) | Persistent PIGN (n = 42) | Healed (n = 28) | p- value |
Interstitial inflammation | |||
Mild/Minimal | 13 (31) | 13 (45) | 0.22 |
Moderate | 14 (33) | 8 (28) | 0.80 |
Marked | 5 (12) | 3 (10) | 1.00 |
No inflammation | 10 (24) | 4 (14) | 0.38 |
Crescents | |||
Fibrocellular | 1 (2) | 0 (0) | 1.00 |
Cellular | 2 (5) | 0 (0) | 0.51 |
Subepithelial humps | 31 (74) | 17 (59) | 0.30 |
Subendothelial deposits | 24 (57) | 2 (7) | <0.0001 |
Mesangial deposits | 34 (81) | 15 (52) | 0.02 |
Immunofluorescence | |||
C3+ Ig | 23 (55) | 10 (34) | 0.15 |
C3+ IgM | 11 (26) | 7 (24) | 1.00 |
C3+ IgG | 2 (5) | 0 (0) | 0.51 |
C3+ IgM+ IgG | 10 (24) | 3 (10) | 0.22 |
C3 only | 8 (19) | 3 (10) | 0.51 |
C3 negative | 8 (19) | 13 (45) | 0.02 |
Interstitial fibrosis | |||
Mild | 14 (33) | 8 (28) | 0.79 |
Moderate | 11 (26) | 9 (31) | 0.60 |
Marked | 7 (17) | 5 (17) | 1.00 |
No fibrosis | 10 (24) | 7 (24) | 1.00 |