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. 2014 Oct 1;9(10):e108398. doi: 10.1371/journal.pone.0108398

Table 3. Summary of pathological findings on 70 patients with persistent and healed PIGN.

Pathological Finding –no of patients (%) Persistent PIGN (n = 42) Healed (n = 28) p- value
Interstitial inflammation
Mild/Minimal 13 (31) 13 (45) 0.22
Moderate 14 (33) 8 (28) 0.80
Marked 5 (12) 3 (10) 1.00
No inflammation 10 (24) 4 (14) 0.38
Crescents
Fibrocellular 1 (2) 0 (0) 1.00
Cellular 2 (5) 0 (0) 0.51
Subepithelial humps 31 (74) 17 (59) 0.30
Subendothelial deposits 24 (57) 2 (7) <0.0001
Mesangial deposits 34 (81) 15 (52) 0.02
Immunofluorescence
C3+ Ig 23 (55) 10 (34) 0.15
C3+ IgM 11 (26) 7 (24) 1.00
C3+ IgG 2 (5) 0 (0) 0.51
C3+ IgM+ IgG 10 (24) 3 (10) 0.22
C3 only 8 (19) 3 (10) 0.51
C3 negative 8 (19) 13 (45) 0.02
Interstitial fibrosis
Mild 14 (33) 8 (28) 0.79
Moderate 11 (26) 9 (31) 0.60
Marked 7 (17) 5 (17) 1.00
No fibrosis 10 (24) 7 (24) 1.00