Table 5. Bacteria taxa with relative proportions correlating significantly with concentration of daidzein and daidzein metabolites.
Phylum | Family | Genus | Daidzein | DHdaidzein | S-(-)Equol | ODMA |
Actinobacteria | Bifidobacteriaceae | Bifidobacterium | −0.559 | 0.179* | ||
Other | −0.410 | 0.438 | ||||
Coriobacteriaceae | Adlercreutzia | −0.451 | ||||
Collinsella | 0.536ψ | |||||
Slackia | −0.464 | |||||
Corynebacteriaceae | Corynebacterium | −0.409 | ||||
Micrococcaceae | Rothia | 0.410ψ | ||||
Other | Other | −0.401 | ||||
Firmicutes | Clostridiaceae | Clostridium | −0.431 | |||
Eubacteriaceae | Pseudoramibacter | 0.398ψ | ||||
Erysipelotrichaceae | Other | 0.451 | ||||
Lachnospiraceae | [Ruminococcus] | −0.407 | ||||
Dorea | 0.407ψ | |||||
Peptostreptococcaceae | Unclassified | −0.438 | −0.466 | |||
Ruminococcaceae | Oscillospira | 0.473ψ | ||||
Other | 0.407 | |||||
Ruminococcus | 0.451 | |||||
Streptococcaceae | Lactococcus | 0.402 | ||||
[Tissierellaceae] | Finegoldia | 0.398ψ | ||||
Peptoniphilus | −0.398ψ | 0.466ψ | ||||
Veillonellaceae | Dialister | 0.524ψ | ||||
Other | Other | 0.401 | ||||
Verrucomicrobia | Other | Other | −0.440 | −0.398 |
Correlations calculated using the non-parametric Kendall’s tau measure and significant if p<0.05.
Full table of correlations with all isoflavone metabolites are available in Table S4.
*Correlation between Bifidobacterium and equol is not significant, reported here to illustrate the negative relationship between dihydrodaidzein and S-(-)equol.
Genera not previously reported to be involved in isoflavone metabolism [7].
Groups listed as unclassified or other cannot be assigned to a genus at this time and therefore isoflavone metabolism is unknown.
DHdaidzein = dihydrodaidzein, ODMA = O-desmethylangolensin.