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. 2014 Oct 1;9(10):e108924. doi: 10.1371/journal.pone.0108924

Table 5. Bacteria taxa with relative proportions correlating significantly with concentration of daidzein and daidzein metabolites.

Phylum Family Genus Daidzein DHdaidzein S-(-)Equol ODMA
Actinobacteria Bifidobacteriaceae Bifidobacterium −0.559 0.179*
Other −0.410 0.438
Coriobacteriaceae Adlercreutzia −0.451
Collinsella 0.536ψ
Slackia −0.464
Corynebacteriaceae Corynebacterium −0.409
Micrococcaceae Rothia 0.410ψ
Other Other −0.401
Firmicutes Clostridiaceae Clostridium −0.431
Eubacteriaceae Pseudoramibacter 0.398ψ
Erysipelotrichaceae Other 0.451
Lachnospiraceae [Ruminococcus] −0.407
Dorea 0.407ψ
Peptostreptococcaceae Unclassified −0.438 −0.466
Ruminococcaceae Oscillospira 0.473ψ
Other 0.407
Ruminococcus 0.451
Streptococcaceae Lactococcus 0.402
[Tissierellaceae] Finegoldia 0.398ψ
Peptoniphilus −0.398ψ 0.466ψ
Veillonellaceae Dialister 0.524ψ
Other Other 0.401
Verrucomicrobia Other Other −0.440 −0.398

Correlations calculated using the non-parametric Kendall’s tau measure and significant if p<0.05.

Full table of correlations with all isoflavone metabolites are available in Table S4.

*Correlation between Bifidobacterium and equol is not significant, reported here to illustrate the negative relationship between dihydrodaidzein and S-(-)equol.

ψ

Genera not previously reported to be involved in isoflavone metabolism [7].

Groups listed as unclassified or other cannot be assigned to a genus at this time and therefore isoflavone metabolism is unknown.

DHdaidzein = dihydrodaidzein, ODMA = O-desmethylangolensin.