Figure 1. Kinetics of pulmonary function parameters post-BMT show that OB manifestations begin as early as 2 weeks.

Lethally conditioned B10.BR mice were given B6 BM with (▪BMS) or without (◊BM) spleen cells. PFTs were done on the days indicated sequentially on the same mice. A. Resistance; B. Compliance. *p<0.05 vs day 0 for BMS (OB) group. #p<0.05 BMS vs BM group. N = 5–40/group/time point pooled from 4 experiments.