Fig. 2.

Transverse slice images through site of ligation in mouse model of myocardial infarction. (a) Optoacoustic image taken at 900 nm. White dotted line indicates the left ventricle. L-region of ligation. RV-right ventricle, LV-left ventricle. Note the dark area around the ligation caused by reduced hemoglobin concentrations. (b) MSOT image. Spectrally unmixed signal from dPGS-NIR (green) superimposed on optacoustic image taken at 900 nm. M-infarcted myocardium. (c) Color photograph of corresponding cryosection (ex vivo) for validation. The ligation is visible. Labels the same as in (a). (d) Near infrared fluorescence (NIRF, green) from dPGS-NIR superimposed on color photograph of cryosection. dPGS-NIR is found in the infarcted myocardium as well as regions in the thoracic wall injured during surgery.