Figure 8. CoQ delays and decreases β-amyloid incorporation into endothelial cells.

HUVECs were incubated for 12 h with vehicle or 5 µM CoQ. Changes in HiLyte Fluor-labeled Aβ_25–35 were monitored by time-lapse microscopy every 30 sec in cells pretreated with PBS or 5 µM CoQ. Fluorescent peptide (5 µM) was added in min 1. Pictures show the variation of fluorescence at different time points, from 0 to 45 min. Graph shows fluorescence dynamics, expressed as normalized relative fluorescence units (RFUs), (n = 3).