Table 3.
Multivariable adjusted associations between bolus versus maintenance (Referent) dosing and infection-related outcomes for the catheter subgroup (N=9,113)
| Outcome | Effect measure 1 | Estimate (95% CI) |
|---|---|---|
| Hospitalized for pneumonia, sepsis, vascular access infection | Hazard Ratio | 1.19 (0.99, 1.44) |
| Rate Difference | 100 (-10, 201) | |
| Hospitalized for infection of any major organ system | Hazard Ratio | 1.15 (0.98, 1.35) |
| Rate Difference | 106 (-19, 223) | |
| Use of intravenous antibiotics | Hazard Ratio | 1.08 (0.96, 1.22) |
| Rate Difference | 126 (-36, 332) | |
| Infection-Related Death | Hazard Ratio | 1.39 (0.74, 2.61) |
| Rate Difference | 11 (-17, 47) | |
| Hospitalized for pneumonia, vascular access infection, sepsis or infection-related death | Hazard Ratio | 1.20 (0.99, 1.44) |
| Rate Difference | 105 (-1.5, 213) | |
| Hospitalized for any infection or use of intravenous antibiotics | Hazard Ratio | 1.07 (0.97, 1.19) |
| Rate Difference | 179 (-45, 431) |
1Rate difference per 1000 patient years.