Table 5.
Odds ratios (OR) and 95% confidence (CIs) intervals for case–control associations with BMI, education and annual income for early and advanced stage ovarian cancer, the African American Cancer Epidemiology Study (AACES), 2010-14†
| Early Stage at Diagnosis (Stage I/II) | Advanced Stage at Diagnosis (Stage III/IV) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Controls (N = 622) | Cases (N = 168) | Cases (N = 182) | ||||||||
| N (%) | N (%) | OR* | (95% CI) | OR** | (95% CI) | N (%) | OR* | (95% CI) | OR** | (95% CI) | |
| Body mass index 1 year before diagnosis (kg/m 2 ) | |||||||||||
| <24.9 | 119 (19.2) | 25 (14.9) | 1.00 | Referent | 1.00 | Referent | 26 (14.4) | 1.00 | Referent | 1.00 | Referent |
| 25–29.9 | 157 (25.3) | 38 (22.6) | 1.10 | (0.63-1.93) | 1.18 | (0.66-2.08) | 50 (27.6) | 1.33 | (0.77-2.27) | 1.31 | (0.76-2.26) |
| 30–34.9 | 157 (25.3) | 51 (30.4) | 1.53 | (0.90-2.62) | 1.56 | (0.90-2.68) | 51 (28.2) | 1.46 | (0.85-2.49) | 1.45 | (0.84-2.48) |
| > = 35 | 188 (30.3) | 54 (32.1) | 1.33 | (0.78-2.26) | 1.33 | (0.78-2.28) | 54 (29.8) | 1.31 | (0.77-2.22) | 1.23 | (0.72-2.09) |
| Missing | 1 | 1 | |||||||||
| Education | |||||||||||
| High school or less | 223 (35.9) | 80 (47.6) | 1.00 | Referent | 1.00 | Referent | 84 (46.2) | 1.00 | Referent | 1.00 | Referent |
| Some post-high school training | 227 (36.6) | 47 (28.0) | 0.60 | (0.40-0.89) | 0.59 | (0.39-0.90) | 62 (34.1) | 0.78 | (0.53-1.14) | 0.84 | (0.56-1.25) |
| College or graduate degree | 171 (27.5) | 41 (24.4) | 0.69 | (0.45-1.06) | 0.65 | (0.41-1.04) | 36 (19.8) | 0.59 | (0.38-0.93) | 0.67 | (0.42-1.09) |
| Missing | 1 | ||||||||||
| Annual Income | |||||||||||
| < $10,000 | 130 (21.2) | 43 (25.9) | 1.00 | Referent | 1.00 | Referent | 37 (20.8) | 1.00 | Referent | 1.00 | Referent |
| $10,000 - < $25,000 | 145 (23.6) | 41 (24.7) | 0.85 | (0.52-1.39) | 0.86 | (0.52-1.43) | 49 (27.5) | 1.15 | (0.70-1.89) | 1.19 | (0.72-1.96) |
| $25,000 - < $50,000 | 131 (21.3) | 41 (24.7) | 0.96 | (0.59-1.58) | 0.96 | (0.58-1.60) | 43 (24.2) | 1.17 | (0.70-1.94) | 1.27 | (0.75-2.13) |
| $50,000 - < $75.000 | 103 (16.8) | 23 (13.9) | 0.68 | (0.38-1.20) | 0.69 | (0.38-1.25) | 23 (12.9) | 0.79 | (0.44-1.42) | 0.91 | (0.49-1.67) |
| ≥ $75,000 | 105 (17.1) | 18 (10.8) | 0.52 | (0.28-0.96) | 0.54 | (0.29-1.02) | 26 (14.6) | 0.90 | (0.51-1.59) | 1.09 | (0.60-1.99) |
| Missing | 8 | 2 | 4 | ||||||||
†Seventeen controls were excluded from this table; 14 cases excluded from the early stage cases and 17 cases excluded from advanced stage cases due to missing data for either parity or months of oral contraceptive use.
*Age adjusted(ORs).
**Multivariable adjusted (ORs) adjusted for age, months of oral contraceptive use, and parity.