Table 4.

Standardized correlation coefficients between OCT measurements and neurologic and visual function parameters in eyes of patients with relapsing-remitting multiple sclerosis, calculated using generalized estimating equations accounting for sex, age, and within-patient intereye correlation (n = 140).

	BCVA	MD	EDSS	Disease duration
Cirrus average pRNFL	0.286∗	0.418∗	−0.014	−0.233‡
Cirrus temporal pRNFL	−0.013	0.062	0.001	−0.141
Spectralis average pRNFL	0.314∗	0.360∗	0.033	−0.228‡
Spectralis temporal pRNFL	0.122‡	0.268†	−0.101	−0.261‡
Spectralis PMB pRNFL	0.125‡	0.209‡	−0.066	−0.275†
GCIPL average	0.226∗	0.513∗	−0.178	−0.262‡
GCIPL minimum	0.204†	0.412∗	−0.161	−0.299†
Non-ON eyes (N = 104)
Cirrus average pRNFL	−0.019	0.098	0.033	−0.253‡
Cirrus temporal pRNFL	−0.270‡	−0.030	−0.046	−0.146
Spectralis average pRNFL	0.210∗	0.145	0.109	−0.274‡
Spectralis temporal pRNFL	−0.025	0.093	−0.092	−0.284†
Spectralis PMB pRNFL	0.002	0.083	−0.040	−0.332†
GCIPL average	−0.062	0.109	−0.113	−0.297‡
GCIPL minimum	0.029	0.138	−0.092	−0.314†
ON eyes (N = 36)
Cirrus average pRNFL	0.188	0.161	−0.173	0.012
Cirrus temporal pRNFL	−0.043	0.001	0.105	−0.013
Spectralis average pRNFL	0.175	0.149	−0.151	0.109
Spectralis temporal pRNFL	0.112	0.030	−0.195	0.065
Spectralis PMB pRNFL	0.059	−0.022	−0.120	0.097
GCIPL average	0.145	0.133	−0.429†	−0.079
GCIPL minimum	0.144	0.120	−0.421‡	−0.227

*P < 0.001; ^† P < 0.01; ^‡ P < 0.05.

OCT: optic coherence tomography; BCVA: best corrected visual acuity; MD: Goldman 24-2 SITA standard visual field mean deviation; EDSS: Expanded Disability Status Scale; pRNFL: peripapillary retinal nerve fiber layer; PMB: papillomacular bundle; GCIPL: ganglion cell and inner plexiform layers; ON: optic neuritis.