Table 2C.
Results of Multivariable Modeling of Risk Factors for Early Onset of Signs and Symptoms: Clinical Characteristicsa
| Cough | Sputum | Clubbing | Crackles | Wheezing | |
|---|---|---|---|---|---|
|
| |||||
| HR (95% CI) |
HR (95% CI) |
HR (95% CI) |
HR (95% CI) |
HR (95% CI) |
|
| Pancreatic enzyme usage before symptom onset | 1.75 (1.47, 2.10) |
2.20 (1.56, 3.10) |
1.64 (1.13, 2.37) |
2.20 (1.44, 3.37) |
|
| Asthma before symptom onset | 1.60 (1.48, 1.73) |
1.45 (1.34, 1.58) |
1.16 (1.06, 1.27) |
1.51 (1.38, 1.66) |
2.95 (2.61, 3.33) |
| Liver disease before symptom onset | 1.28 (1.12, 1.46) |
1.23 (1.08, 1.41) |
|||
| ABPA before symptom onset | 1.68 (1.25, 2.24) |
1.91 (1.26, 2.89) |
|||
| HI before symptom onset | 1.15 (1.06, 1.26) |
||||
| SA before symptom onset | 1.23 (1.15, 1.32) |
1.36 (1.20, 1.54) |
1.35 (1.20, 1.53) |
1.37 (1.18, 1.59) |
|
| PA before symptom onset | 1.53 (1.41, 1.65) |
2.06 (1.80, 2.35) |
1.38 (1.20, 1.58) |
2.01 (1.72, 2.36) |
1.37 (1.21, 1.55) |
| SA + PA concurrently before symptom onset | 0.86 (0.77, 0.96) |
1.21 (1.07, 1.37) |
1.39 (1.20, 1.61) |
||
| SA and PA (not necessarily concurrent) before symptom onset | 0.74 (0.61, 0.89) |
0.80 (0.67, 0.94) |
0.74 (0.59, 0.92) |
||
a
Statistically significant predictors included in any of the five models had P < 0.01.
ABPA, allergic bronchopulmonary aspergillosis; CI, confidence interval; HI, Haemophilus influenzae; HR, hazard ratio; PA, Pseudomonas aeruginosa; SA, Staphylococcus aureus.