Table I.

 Algorithm for Hypertension Management

Step	Medication	Minimal Starting Dose	Usual Starting Dose	Titration Sequence
1	Lisinopril or	10 mg po QD	10 mg po QD	10–20–40 mg po QD
	Losartan	50 mg po QD	50 mg po QD	50 mg po QD
2	Lisinopril/HCTZ or	10/12.5 mg po QD	20/12.5 mg po QD	10/12.5–40/25 mg po QD
	Losartan/HCTZ	50/12.5 mg po QD	50/12.5 mg po QD	50/12.5–100/25 mg po QD
3	Atenolol or	25 mg po QD	50 mg po QD	25–50–100 mg po BID
	Nifedipine	30 mg po QD	30 mg po QD	30–60–90 mg po QD
4	Add alternate #3 agent at specified doses: if no atenolol, can add nifedipine and vice versa.
5	Doxazosin	1 mg po QD	1 mg po QD	1–2–3–4–5–6–7–8 mg po QD
6	Hydralazine or	25 mg po BID	25 mg po BID	25–50–100 mg po BID
	Minoxidil or	2.5 mg po BID	2.5 mg po BID	2.5–5–10–20 mg po BID
	Reserpine	0.1 mg po QD	0.1 mg po QD	0.1–0.2–0.3 mg po QD

Abbreviations: BID, twice a day; po, orally; HCTZ, hydrochlorothiazide; QD, every day.