Table II.
Aggressive Group | Standard Group | P Value a | |
---|---|---|---|
No. randomized | 276 | 272 | |
Arizona (Phoenix) | 70 | 68 | |
Arizona (Chinle) | 63 | 73 | |
Oklahoma | 71 | 66 | |
Dakota | 72 | 65 | |
Sex | |||
Male | 101 | 101 | |
Female | 171 | 175 | .90 |
Age, y | 55.8 (9.3)b | 57.4 (9.3) | .04 |
Body mass index, kg/m2 | 33.5 (6.5) | 33.0 (6.1) | .41 |
Diabetes duration, y | 10.3 (8.4) | 9.8 (8.4) | .52 |
Hypertension duration, y | 10.1 (8.6) | 10.6 (8.7) | .61 |
SBP, mm Hg | 128.7 (14.7) | 132.6 (16.4) | .003 |
DBP, mm Hg | 74.1 (10.4) | 75.9 (10.4) | .04 |
Pulse pressure, mm Hgc | 54.6 (13.4) | 56.7 (14.2) | .08 |
Mean arterial pressure, mm Hgd | 92.2 (10.3) | 94.8 (10.8) | .01 |
Blood urea nitrogen, mg/dL | 15.5 (5.6) | 15.5 (5.7) | .93 |
Serum creatinine, mg/dL | 0.85 (0.25) | 0.86 (0.23) | .44 |
Estimated GFR (MDRD), mL/min/1.73 m2 | 89.7 (24.3) | 87.1 (23.3) | .20 |
Albuminuria, % | |||
Normal | 91.1 (87.0–95.1) | 87.7 (82.9–92.5) | |
Microalbuminuria | 8.4 (4.5–12.4) | 11.7 (7.0–16.4) | |
Macroalbuminuria | 0.5 (−0.5 to 1.6) | 0.6 (−0.5 to 1.7) | .65 |
Left ventricular hypertrophy, % | 24.2 (19.0–29.3) | 19.4 (14.6–24.2) | .18 |
Abbreviations: DBP, diastolic blood pressure; GFR, glomerular filtration rate; MDRD, Modification of Diet in Renal Disease study group; SBP, systolic blood pressure. a T test/Chi‐square test/Fisher exact test was used to calculate the P value. bNumbers in parentheses are one standard deviation for continuous variables and 95% confidence interval for percentages. cPulse pressure = SBP – DBP. dMean arterial pressure=[(2*DBP) + SBP]/3.