Table 2.
Overview of the most significantly overrepresented KEGG pathways and GO terms associated with the modules detected using WGCNA
| WGCNA module | KEGG pathway or GO-term | Frequency in module | Number of genes in term | P adj |
|---|---|---|---|---|
|
Blue |
KEGG: Osteoclast differentiation |
12 |
52 |
1.40E-07 |
| |
KEGG: Natural Killer cel mediated cytotoxity |
8 |
34 |
3.76E-05 |
| |
KEGG: B cell receptor signaling pathway |
7 |
29 |
7.24E-05 |
| |
GO: Immune system response |
39 |
516 |
5.57E-11 |
| |
GO: Cell activation |
26 |
217 |
2.53E-10 |
| |
GO: Regulation of immune system response |
28 |
82 |
1.22E-09 |
|
Black |
GO: Extracellular region |
40 |
382 |
5.53E-06 |
| |
GO: Extracellular matrix |
21 |
121 |
3.61E-05 |
| |
GO: Proteinaceous extracellular matrix |
19 |
97 |
3.61E-05 |
|
Lightyellow |
GO: Nucleolus |
8 |
124 |
1.30E-02 |
| |
GO: Ribosome biogenesis |
4 |
18 |
3.40E-02 |
| GO: Nuclear par | 12 | 437 | 3.40E-02 |