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Average horizontal activity counts/10 min (± SE) during the 30 min of peak effect as a function of dose for each of the six cathinones (panels left to right). Data are from independent groups of 8 mice per dose. All of the cathinones increased ambulation (* indicates p < 0.05 against vehicle control) and showed an inverted U-shaped dose response († indicates depressant effects p < 0.05 against vehicle control.
