TABLE 10.
MPL-regulated probe sets related to cell fates
| 230A probe set | 230A accession | U34A probe set/accession | Symbol | Identification | Response
|
|
|---|---|---|---|---|---|---|
| Acute | Chronic | |||||
| 1374595, 1376999 | BF389721 | AA892570 | Tnks2 | Tankyrase, telomeric repeat-binding factor 1 | Up | Up |
| 1388953 | AA892598 | AA800679, AA892598 (2) | GNL3 | Guanine nucleotide binding protein-like 3 (nucleolar), stem cell proliferation | Up | Up |
| 1370163 | BF281299 | J04791 | Odc1 | Ornithine decarboxylase 1 | Up | Up |
| 1370575 | D50734 | AI043631 | Oazin | Ornithine decarboxylase antizyme inhibitor | Up | Up |
| 1370807 | AF411216 | AA859954 | Vacuole membrane protein 1 (apoptosis) | Up | Up | |
| 1367764 | NM_012923 | X70871 | Ccng1 | Cyclin G1 | Up | Up |
| 1388395 | AI406939 | AA893235 | GOS2 | G0/G1 switch gene 2 | Down/up | Up |
| 1367847 | NM_053611 | NM_053611 | Nupr1, p8 | Nuclear protein 1 (cell proliferation) | Down/up | Up |
| 1389179 | BF284899 | AA800243 | DFF | Cell death-inducing DNA fragmentation factor | Down/up | Up |
| 1371643 | AW143798 | X75207 | CCND1 | CCND1 gene; cyclin D1 | Down | Down |
| 1368311 | NM_012861 | M76704 | MGMT | O6-Methylguanine-DNA methyltransferase (DNA repair) | Down | Down |
| 1371684 | AA799330 | AA799330 | Pelota homolog (cell division) | Up | Down | |
Probe sets regulated by MPL in rat liver after both acute and chronic drug administration and categorized as relating to cell fates (proliferation, differentiation, or apoptosis). Affymetrix 230A arrays use a probe set number distinct from GenBank accession numbers, whereas U34A chips use a common probe set/GenBank accession number for identification.