TABLE 11.
230A probe set | 230A accession | U34A probe set/accession | Symbol | Identification | Response
|
|
---|---|---|---|---|---|---|
Acute | Chronic | |||||
1386864, 1369473 | NM_053290 | AI169417, U20195 | Pgam1 | Phosphoglycerate mutase 1 (glycolytic) | Up | Up |
1387052 | NM_031039 | D10354 | Gpt | Glutamic pyruvic transaminase 1, soluble | Down/up | Up |
1369560, 1371363 | NM_022215 | AB002558 | Gpd3 | Glycerol-3-phosphate dehydrogenase 1 (soluble) | Down | Up |
1370299 | M10149 | AA892395 | Aldob | Aldolase B | Down | Up |
1369635 | NM_017052 | X74593, AI030175 | Sord | Sorbitol dehydrogenase | Down | Down |
1373337 | AI412065 | AA892799, AA892799, AA892799 | Glyoxylate reductase/hydroxypyruvate reductase | Down | Down | |
1370870, 1370067 | NM_012600 | AI171506, M26594, AI171506, AI008020 | Me1 | Malic enzyme 1 (cytosolic) | Down | Down |
1369954 | NM_031510 | AA892314 | IDH1 | Isocitrate dehydrogenase 1, soluble | Down | Down |
1370725, 1386944 | NM_013098 | L37333 | G6pc | Glucose-6-phosphatase, catalytic | Down | Down/up |
1387312 | NM_012565 | X53588 | Gck | Glucokinase | Down/up | Down/up |
Probe sets regulated by MPL in rat liver after both acute and chronic drug administration and categorized as relating to carbohydrate metabolism. Affymetrix 230A arrays use a probe set number distinct from GenBank accession numbers, whereas U34A chips use a common probe set/GenBank accession number for identification.