TABLE 5.
Immune-related MPL-regulated probe sets
| 230A probe set | 230A accession | U34A probe set/accession | Symbol | Identification | Response
|
|
|---|---|---|---|---|---|---|
| Acute | Chronic | |||||
| 1398784 | NM_019259 | AI178135 | C1qbp | C1q binding, inhibits C1 activation | Up | Up |
| 1390104 | BI296551 | AI010580 | Irgq | Immunity-related GTPase family, Q | Up | Up |
| 1388331 | BG057543 | AA685903 | Tumor rejection antigen gp96 | Up | Up | |
| 1375686 | AI706907 | AA892680, AA892298 | Ppil3 | Peptidylprolyl isomerase (cyclophilin)-like 3 | Up | Up |
| 1367657 | NM_017258 | L26268 (2) | Btg1 | B-cell translocation gene 1, antiproliferative | Up | Up |
| 1368668 | NM_053866 | U17901 | Plaa | Phospholipase A2, activating protein | Up | Up |
| 1370750, 1369255 | NM_013123 | M95578 (2), U14010 (2) | Il1r1 | IL-1 receptor, type I | Up | Up |
| 1371926, 1373140, 1370957 | BM383427 | M92340 | Il6st | IL-6 signal transducer | Up | Up |
| 1386987 | NM_017020 | M58587 | Il6r | IL-6 receptor | Up | Up |
| 1372926 | AI009159 | U27201 | TIMP-3 | Tissue inhibitor of metalloproteinase 3 | Up | Up |
| 1370855 | BG666933 | AI231292 | Cst3 | Cystatin C (inhibitor of cysteine proteinases) cathepsins | Down | Up |
| 1387127 | NM_031351 | AA859645 | Atrn, DPPT-L | Attractin | Down | Up |
| 1398256 | NM_031512 | M98820 | Il1b | IL-1β | Down | Down |
| 1374334 | AI412189 | AI234828 | Ig heavy chain V-III region VH26 precursor | Down | Down | |
| 1371100 | AA859049 | D00362, M20629 | Es2 | Esterase 2 | Down | Down |
| 1368755 | NM_053753 | M55532 | Kclr | C-type (calcium dependent) lectin, superfamily member 13 | Down | Down |
| 1368741 | NM_057146 | U52948 | C9 | Complement component C9 | Down | Down |
| 1373025 | AI411618 | AA891576 | Complement protein C1q β chain | Down | Down | |
| 1370027, 1388229 | M22359, NM_023103 | M22360, M22359 | Mug1 | Murinoglobulin 1 homolog, plasma proteinase inhibitor α-1-inhibitor III | Down | Down |
| 1371015 | X52711 | X52711 | Mx1 | Myxovirus (influenza virus) resistance 1 | Up/down | Down |
| 1370056 | NM_020103 | M30691 | Ly6c | Ly6-C antigen | Up/down | Down |
| 1368332 | NM_133624 | M80367 | Gbp2 | Guanylate nucleotide binding protein 2 | Up/down | Down |
| 1367614 | NM_012904 | S57478, AI171962 | Anxa1 | Annexin A1, lipocortin I | Up/down | Down |
| 1368073 | NM_012591 | M34253 (2) | Irf1 | Interferon regulatory factor 1 | Up/down | Down |
| 1368592, 1371170 | AJ245643, NM_017019 | D00403 | Il1a | IL-1α (Il1a) | Up/down | Down |
| 1367679 | NM_013069 | X13044 | INVG34 | Histocompatibility: class II antigens, γ-chain of | Up/down | Down |
| 1383564 | BF411036 | AA799861(2) | Irf7 | Interferon regulatory factor 7 | Up | Down |
| 1398246 | NM_053843 | M32062 (2) | Fcgr3 | Fc receptor, IgG, low affinity III | Up | Down |
| 1387687 | NM_133542 | AJ223184 | Igsf6 | Ig superfamily, member 6 | Up | Down |
| 1367574 | NM_031140 | X62952 | Vim | Vimentin | Up | Down |
| 1376151 | AI407953 | AA891944 | Interferon-γ-induced GTPase | Down/up | Down | |
Probe sets regulated by MPL in rat liver after both acute and chronic drug administration and categorized as immune related. Affymetrix 230A arrays use a probe set number distinct from GenBank accession numbers, whereas U34A chips use a common probe set/GenBank accession number for identification.