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The genetics and predicted structure of formate hydrogenlyase. (A) The genetic organization of the E. coli hycABCDEFGHI operon and the fdhF gene. Genes colored gray do not encode components of the final enzyme. The gene encoding the catalytic subunit of Hyd-3 is indicated. (B) Predicted architecture of the E. coli FHL complex. Proteins are color-coded corresponding to their respective genes from A. (C) Cartoon of E. coli Complex I color-coded to highlight similarity with FHL.
