Skip to main content
. 2014 Oct 2;10(10):e1003712. doi: 10.1371/journal.pcbi.1003712

Table 1. Summary of multi-resolution methods for network diagnostics.

Technique Method Summary Control Parameter Strengths and Limitations Refs.
Soft Threhsolding Raise each entry in Inline graphic to the power r:Inline graphic r: power applied to entries in Inline graphic. Small r limit weights all connections equally. Large r limit amplifies strong connections, relative to weak. Enables continuous variation of the contribution of edges of different weights. Strong edges may dominate, but all connections retained. [49], [50]
Windowed Thresholding Construct binarized network a fixed percentage of connections corresponding to a range of edge weights Inline graphic: average edge weight of connections within the window. Small Inline graphic isolates weak connections. Large Inline graphic isolates strong connections. Enables an isolated view of structure at different edge weights. Weak connections are not obscured by strong connections, but relationships between strong and weak connections are ignored. [15], [49]
Modularity Resolution Structural resolution tuned in community detection. Sets a tolerance on the partition into modules relative to a null model. Inline graphic: appears in the quality function Inline graphic or Inline graphic optimized when dividing nodes into partitions. Small Inline graphic yields one large community. Large Inline graphic yields many small communities. Enables a continuous variation in the resolution of community structure. This method has the most direct, tunable control of the output, but does not generalize to diagnostics other than those associated with modularity. [51]

We use soft thresholding, windowed thresholding, and variation in the resolution parameter of modularity maximization to probe network architecture across scales (Column 1). For each approach, we provide a method summary (Column 2), a description of the control parameter (Column 3), a brief synopsis of the strengths and limitations of the approach (Column 4), and a few relevant references (Column 5).