Table 4.
Adverse drug reactions in 110 MDR-TB patients in the study
| Entire population (N = 110) | HIV-negative (N = 83) | HIV-positive (N = 27) | P value | |
|---|---|---|---|---|
| Gastrointestinal distress | 12 (10.9) | 9 (10.8) | 3 (11.1) | 0.969 |
| Neuropsychiatric disturbance | 18 (16.4) | 11 (13.3) | 7 (25.9) | 0.122 |
| Ototoxicity | 12 (10.9) | 11 (13.3) | 1 (3.7) | 0.167 |
| Nephrotoxicity | 3 (2.7) | 1 (1.2) | 2 (7.4) | 0.086 |
| Hypothyroidism | 5 (4.5) | 5 (6.0) | 0 (0) | 0.192 |
| Arthralgia | 14 (12.7) | 12 (14.5) | 2 (7.4) | 0.34 |
| Gynecomastia | 4 (3.6) | 4 (4.8) | 0 (0) | 0.245 |
| Peripheral neuropathy | 15 (13.6) | 13 (15.7) | 2 (7.4) | 0.278 |
| Dermatologic | 5 (4.6) | 5 (6.0) | 0 (0) | 0.192 |