Figure 1.

Histopathologic evaluation of tissue specimens collected post-mortem from an individual (Case 2) that died in Puerto Rico in 2010 following co-infection with Leptospira species and dengue virus-type 4. Tissue specimens were taken from the lung (A) and kidney (B and C) and stained with hemotoxylin-eosin (A and B; original magnification 10× and 20×, respectively) or probed with polyclonal anti-Leptospira antibody for immunohistochemical detection of Leptospira antigen (C; arrowheads indicate antigen; original magnification 63×).