Table 2. Phenotype of melarsoprol resistant strains.
10 mg/kg BW | 10 mg/kg BW (rep) | 12 mg/kg BW | ||||
Alias name | numbers relapsed | DPI | numbers relapsed | DPI | numbers relapsed | DPI |
15BT | 2 | 85* | 0 | na | 0 | na |
163AT | 3 | 88* | 1 | 28 | 1 | 31 |
346AT | 1 | 90* | 6 | 20 | 6 | 20* |
Number of relapsing mice (out of 6 infected) and day post-infection that relapses were observed after treatment with melarsoprol at different dosages and repetitions. DPI: days post-infection, BW: body weight, rep: repetition, na: not applicable,
*: relapsing population used for AQP2/3 RFLP analysis.