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. 2014 Oct 2;8(10):e3198. doi: 10.1371/journal.pntd.0003198

Figure 1. Induction of IFNγ in SLA stimulated whole blood and splenic aspirates from patients with active VL.

Figure 1

a) IFNγ in SLA stimulated (black bars) and unstimulated (white bars) WB during the first 24 hours of culture and b) IFNγ production (measured in units by QuantiFeron kit) in culture supernatants from SLA stimulated WB after 24 hours, 72 hours and 5 days incubation at 37°C, 5%CO2. c) IFNγ in 24 hour cultures of SLA stimulated and unstimulated SA from patients with active VL (n = 15) and d) IL-10 in 24-hour SLA stimulated and unstimulated SA (left) and WB (right), n = 8. Results show in a mean OD+SD of the samples tested, in b–d one dot represents one sample. Stimulated and unstimulated samples were compared by Wilcoxon matched paired test and statistical significances are indicated with *** p<0.001, ** p<0.01 and * p<0.05.