Table 3. Results of ROC analysis of selected markers for discrimination between Stage AB and CD among T. cruzi-infected individuals.
| Biomarker | AUC (95% CI) | Selected cut-point | Sensitivity | Specificity |
| BNP | 0.65 (0.57–0.73) | 103.64 pg/ml | 60.0% | 60.4% |
| NTproBNP | 0.78 (0.71–0.85) | 287.83 pg/ml | 72.9% | 72.6% |
| Troponin I | 0.63 (0.55–0.70) | 174.97 pg/ml | 61.2% | 62.3% |
| MMP-2 | 0.65 (0.57–0.73) | 93311 pg/ml | 60.2% | 65.4% |
| TIMP-1 | 0.62 (0.53–0.71) | 154120 pg/ml | 66.2% | 56.7% |
| TIMP-2 | 0.62 (0.53–0.71) | 88677 pg/ml | 63.4% | 67.8% |
| Biomarker Ratios | ||||
| MMP-2/MMP-9 | 0.61 (0.53–0.69) | 0.45 pg/ml | 61.5% | 54.2% |
| MMP-2/TGFB1 | 0.65 (0.57–0.73) | 3.37 pg/ml | 60.9% | 65.1% |