Table 5. Metabolites in lipid extracts from the mouse liver that were significantly different between the normal and UVB groups after 6 weeks and were tentatively identified using nanomate LTQ-MS analysis.
ID | m/z (+) | Adduct | Fold changea | VIPb | p value |
LPC 16∶0 | 496.5 | [M+H]+ | 0.75 | 2.83 | 0.004 |
LPC 18∶1 | 522.5 | [M+H]+ | 0.63 | 1.95 | 0.001 |
LPC 18∶0 | 524.5 | [M+H]+ | 0.63 | 2.68 | <0.001 |
LPC 20∶4 | 544.4 | [M+H]+ | 0.74 | 1.17 | 0.019 |
LPC 20∶3 | 546.5 | [M+H]+ | 0.66 | 0.81 | 0.014 |
LPC22∶6 | 568.5 | [M+H]+ | 0.69 | 1.16 | 0.006 |
PE 34∶2 | 716.5 | [M+H]+ | 1.16 | 0.76 | 0.030 |
PC 32∶0 | 734.6 | [M+H]+ | 1.10 | 1.02 | 0.028 |
PE 36∶4 | 740.5 | [M+H]+ | 1.06 | 0.82 | 0.022 |
PE 36∶2 | 744.5 | [M+H]+ | 1.11 | 0.75 | 0.043 |
PC 32∶0 | 756.6 | [M+Na]+ | 1.21 | 1.44 | 0.005 |
PC 34∶2 | 758.6 | [M+H]+ | 1.23 | 6.49 | <0.001 |
PE 38∶6 | 764.5 | [M+H]+ | 1.18 | 3.14 | <0.001 |
PE 38∶5 | 766.5 | [M+H]+ | 1.09 | 1.49 | 0.006 |
PC 34∶6 | 772.6 | [M+Na]+ | 1.13 | 1.04 | 0.002 |
PC 34∶3 | 778.6 | [M+Na]+ | 1.15 | 0.75 | 0.005 |
PE 39∶6 | [M+H]+ | ||||
PE 38∶5 | 788.7 | [M+Na]+ | 0.93 | 1.19 | 0.030 |
PE 39∶0 | 790.5 | [M+H]+ | 1.11 | 1.40 | 0.005 |
PC 35∶1 | 796.6 | [M+Na]+ | 1.20 | 2.48 | 0.018 |
PE 39∶5 | 802.6 | [M+Na]+ | 1.15 | 0.97 | 0.002 |
PE 39∶0 | 812.7 | [M+Na]+ | 0.90 | 1.95 | 0.004 |
PE 40∶6 | 814.6 | [M+Na]+ | 0.92 | 0.87 | 0.008 |
PC 38∶4 | 832.8 | [M+Na]+ | 0.92 | 1.50 | 0.045 |
PC 38∶3 | 834.8 | [M+Na]+ | 0.89 | 2.32 | 0.010 |
PC 38∶2 | 836.8 | [M+Na]+ | 0.90 | 1.18 | 0.004 |
TG 56∶4 | 928.6 | [M+NH4]+ | 0.74 | 0.82 | 0.048 |
Variables were selected by VIP value (>0.7) and p value (<0.05) from OPLS-DA models.
Fold change was calculated by dividing the mean of the peak intensity of each metabolite from the UVB-radiated group by that of the normal group.
VIP, variable important in the projection.