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. 2014 Oct 2;9(10):e109479. doi: 10.1371/journal.pone.0109479

Table 5. Metabolites in lipid extracts from the mouse liver that were significantly different between the normal and UVB groups after 6 weeks and were tentatively identified using nanomate LTQ-MS analysis.

ID m/z (+) Adduct Fold changea VIPb p value
LPC 16∶0 496.5 [M+H]+ 0.75 2.83 0.004
LPC 18∶1 522.5 [M+H]+ 0.63 1.95 0.001
LPC 18∶0 524.5 [M+H]+ 0.63 2.68 <0.001
LPC 20∶4 544.4 [M+H]+ 0.74 1.17 0.019
LPC 20∶3 546.5 [M+H]+ 0.66 0.81 0.014
LPC22∶6 568.5 [M+H]+ 0.69 1.16 0.006
PE 34∶2 716.5 [M+H]+ 1.16 0.76 0.030
PC 32∶0 734.6 [M+H]+ 1.10 1.02 0.028
PE 36∶4 740.5 [M+H]+ 1.06 0.82 0.022
PE 36∶2 744.5 [M+H]+ 1.11 0.75 0.043
PC 32∶0 756.6 [M+Na]+ 1.21 1.44 0.005
PC 34∶2 758.6 [M+H]+ 1.23 6.49 <0.001
PE 38∶6 764.5 [M+H]+ 1.18 3.14 <0.001
PE 38∶5 766.5 [M+H]+ 1.09 1.49 0.006
PC 34∶6 772.6 [M+Na]+ 1.13 1.04 0.002
PC 34∶3 778.6 [M+Na]+ 1.15 0.75 0.005
PE 39∶6 [M+H]+
PE 38∶5 788.7 [M+Na]+ 0.93 1.19 0.030
PE 39∶0 790.5 [M+H]+ 1.11 1.40 0.005
PC 35∶1 796.6 [M+Na]+ 1.20 2.48 0.018
PE 39∶5 802.6 [M+Na]+ 1.15 0.97 0.002
PE 39∶0 812.7 [M+Na]+ 0.90 1.95 0.004
PE 40∶6 814.6 [M+Na]+ 0.92 0.87 0.008
PC 38∶4 832.8 [M+Na]+ 0.92 1.50 0.045
PC 38∶3 834.8 [M+Na]+ 0.89 2.32 0.010
PC 38∶2 836.8 [M+Na]+ 0.90 1.18 0.004
TG 56∶4 928.6 [M+NH4]+ 0.74 0.82 0.048

Variables were selected by VIP value (>0.7) and p value (<0.05) from OPLS-DA models.

a

Fold change was calculated by dividing the mean of the peak intensity of each metabolite from the UVB-radiated group by that of the normal group.

b

VIP, variable important in the projection.