Table 3.
Treatment | Tissue | ||||
---|---|---|---|---|---|
Liver | Kidney | Lung | Heart | Brain | |
α-T | 19% ± 2%a | 49% ± 6%b | 58% ± 3%b,c | 8% ± 1%*,d | 85% ± 3%e |
Vehicle | 20% ± 2%a | 61% ± 6%b | 52% ± 2%b,c | 18% ± 1%#,a,d | 90% ± 1%e |
Saline | 20% ± 1%a | 54% ± 4%b | 48% ± 2%b,c | 24% ± 4%#,a,d | 90% ± 1%e |
Shown are the mean ± SEM of the %conversion to MK-4 [%=100 × d4-MK-4/(sum (d4-MK-4+ d4-PK)]. Two-factor repeated measures ANOVA P-value: Interaction P<0.0001, different symbols (*,#) in the same column, or different letters in the same row are significantly different, (P<0.05, TMC)