Table 1. Cytokine secretion from HS5 cells after transfecting with siRNA for CDCP1 or Luciferase (control).
siRNA-CDCP1 (pg/mL) | Control siRNA (pg/mL) | Fold | P value | |
G-CSF | 15050+/−1626 | 5950+/−1904 | 2.5 | 0.003 |
GM-SF | 1553+/−178 | 1205+/−114 | 1.3 | 0.04 |
IL-1a | 145+/−10 | 97+/−4 | 1.5 | 0.007 |
IL-1b | 97+/−11 | 23+/−1 | 4.2 | 0.0003 |
IL-8 | 34539+/−5388 | 9741+/−2593 | 3.5 | 0.001 |
IL-6 | 2203+/−244 | 2478+/−134 | 0.9 | N.S. |
VEGF | 1905+/−191 | 1846+/−158 | 1.0 | N.S. |