. 2014 Sep 10;136(38):13194–13197. doi: 10.1021/ja508165a

Table 3. C(sp³)–H Alkylation^a^,^b.

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Conditions: 0.1 mmol of 1i, 2.5 equiv of 2, 10 mol % of Pd(TFA)₂, 20 mol % of L13, 3.0 equiv of AgOPiv, 0.5 mL of DCE, 80 °C, under air, 20 h.

Isolated yields.

The ee value was determined by HPLC analysis on a chiral stationary phase (SI).

Using L1 instead of L13.

1.0 mmol scale.

Table 3. C(sp3)–H Alkylationa,b.