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. 2014 Aug 19;136(37):13029–13037. doi: 10.1021/ja506611k

Table 4. Efficiency and Enantioselectivity of 1, 5, 6b6i, and ent-7 in ARCM of 13.

graphic file with name ja-2014-06611k_0009.jpg

entry catalyst conversion (%)a ee (%)b
1 ent-7 <2 ND
2 6b >98 42
3 6c 35 36
4 6d 35 53
5 6e 76 46
6 6f >98 18
7 6g >98 42
8 6h 48 43
9 6i 72 40
10 5 >98 54
11 1 20 0
a

Determined by 1H NMR spectroscopy;

b

Determined by chiral SFC analysis