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. 2014 Sep 5;136(37):12848–12851. doi: 10.1021/ja507168t

Table 1. GLP-1R Activation, Monitored by cAMP Production for GLP-1(7-36)-NH2 and Analogues.

  EC50 (nM) max response (% GLP-1 max)
GLP-1 1.6 ± 0.2 100
1 >100
2 0.7 ± 0.1 100
3 2.0 ± 0.1 85
4 4.0 ± 0.5 103
5 >100
6 3.2 ± 0.3 88
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