Table 3.
Odds ratios from multivariate logistic regression analysis for presence of any retinopathy of prematurity (ROP) based on weight subgroups (birth weight <500g, 500–749g, 1251–1500g, >1500g).
Whole cohort (N= 1354) |
<500g (N= 15) |
500–749g (N= 223) |
1251–1500g (N= 293) |
>1500g (N= 183) |
|
---|---|---|---|---|---|
Risk Factor | Odds ratios and (95% Confidence interval) | ||||
Female | * | * | * | * | * |
Birth Weight (100g) | 0.819 (.740, .905)† | * | * | * | * |
Gestational age | 0.738 (0.676, 0.805)† | * | * | 0.660 (0.571, 0.843)† | * |
Multiple gestation | * | * | * | * | * |
Assisted conception | 1.720 (1.207, 2.453)† | * | 8.957 (1.154, 69.543)† | * | * |
Mechanical ventilation | * | * | 1.996 (1.024, 3.891)† | * | * |
Sepsis | 2.466 (1.498, 4.060)† | * | 5.015 (1.118, 22.505)† | * | * |
Intraventricular hemorrhage | * | * | * | * | * |
Bronchopulmonary dysplasia | 3.301 (1.534, 7.103)† | * | * | * | * |
Necrotizing enterocolitis | * | * | * | * | * |
Race/Ethnicity‡: | |||||
Black non-Hispanic | 0.484 (0.321, 0.729)† | * | * | 0.394 (0.128, 1.214) | * |
Hispanic | 2.883 (1.639, 5.072)† | * | * | 1.688 (0.520, 5.476) | * |
Asian | 1.255 (0.738, 2.136) | * | * | 0.347 (0.073, 1.643) | * |
Other race/ethnicity | 0.501 (0.353, 0.712)† | * | * | 0.362 (0.141, 0.930)† | * |
Variable entered in the model but excluded from final regression equation.
Statistically significant at the p < 0.05 level.
Odds ratios for race/ethnicity are compared to reference category White, non-Hispanic.
Eleven clinical and demographic risk factors were modeled as discrete variables (presence or absence) except for gestational age (GA, continuous variable with odds ratio calculated per 1-week increase), birth weight (BW, continuous variable with odds ratio calculated per 100-gram increase), and race/ethnicity (categorical variable).