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. Author manuscript; available in PMC: 2015 Jan 24.
Published in final edited form as: N Engl J Med. 2014 Jun 15;371(4):313–325. doi: 10.1056/NEJMoa1314474

Figure 4. Histogram Distributions of Mean Glucose Levels and Insulin Doses among Adults and Adolescents.

Figure 4

Panel A shows a histogram distribution of the mean glucose levels on continuous monitoring in adults during the bionic-pancreas period and the control period. The distribution shows the number of patients with mean glucose levels divided into intervals of 7 mg per deci-liter on days 2 through 5. The dashed red line indicates a mean glucose level of 154 mg per deciliter, which corresponds to a glycated hemoglobin level of 7%. Panel B shows a similar histogram distribution of total daily doses of insulin in the adults, divided into intervals of 0.1 U per kilogram of body weight per day. Panels C and D show similar histogram distributions for the adolescents, with a cutoff point for the mean glucose level of 168 mg of glucose per deciliter, which corresponds to a glycated hemoglobin level of 7.5%. To convert the values for glucose to millimoles per liter, multiply by 0.05551.