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HDAC3 regulates the expression of multiple miRNAs. A, expression level of each miRNA was determined by qRT-PCR. ***, p < 0.005. B shows potential binding sites of various transcriptional factors in miR-200b, miR-217, or miR-335 promoter sequences. C, cell lysates were subjected to ChIP assays employing anti-HDAC3 antibody (2 μg/ml) or IgG antibody (2 μg/ml).
