Table 2. Univariate Cox proportional hazards analysis.
| |
|
|
|
95% CI |
|
|---|---|---|---|---|---|
| Variable | Categories | P-value | Hazard ratio | Lower | Upper |
|
Univariate analysis for RCC DSS | |||||
| Age | Scale | 0.074 | 1.036 | 0.997 | 1.076 |
| Gender | Male vs female | 0.758 | 0.867 | 0.035 | 2.149 |
| Tumour size | Scale | <0.001 | 1.319 | 1.170 | 1.488 |
| T-stage | pT3/4 vs pT1/2 | <0.001 | 14.276 | 4.457 | 53.405 |
| Metastasis | N+M+ vs N0M0 | <0.001 | 11.905 | 4.881 | 29.037 |
| Necrosis | Present vs absent | 0.009 | 3.235 | 1.338 | 7.821 |
| Pelvicalyceal invasion | Present vs absent | 0.015 | 3.281 | 1.255 | 8.574 |
| Microvascular invasion | Present vs absent | <0.001 | 5.397 | 2.148 | 13.560 |
| Sarcomatoid features | Present vs absent | 0.548 | 1.565 | 0.364 | 6.726 |
| Fuhrman grade | G3/4 vs G1/2 | 0.042 | 3.121 | 1.043 | 9.340 |
| 9p status | Deletion vs no deletion | 0.001 | 6.089 | 2.047 | 18.115 |
| SSIGN score |
5 Subcategories |
<0.001 |
3.207 |
2.022 |
5.068 |
|
Univariate analysis for RFS | |||||
| Age | Scale | 0.007 | 1.065 | 1.018 | 1.114 |
| Gender | Male vs female | 0.947 | 1.035 | 0.376 | 2.853 |
| Tumour size | Scale | 0.107 | 1.167 | 0.967 | 1.409 |
| pT-stage | pT3/4 vs pT1/2 | 0.004 | 4.334 | 1.603 | 11.722 |
| Necrosis | Present vs absent | 0.160 | 2.026 | 0.757 | 5.417 |
| Pelvicalyceal invasion | Present vs absent | 0.285 | 1.996 | 0.562 | 7.098 |
| Microvascular invasion | Present vs absent | 0.048 | 2.731 | 1.011 | 7.376 |
| Sarcomatoid features | Present vs absent | 0.213 | 2.584 | 0.581 | 11.502 |
| Fuhrman grade | G3/4 vs G1/2 | 0.222 | 1.940 | 0.669 | 5.622 |
| 9p status | Deletion vs no deletion | 0.008 | 4.642 | 1.494 | 14.421 |
Abbreviations: CI=confidence interval; DSS=disease-specific survival; RCC=renal cell carcinoma; RFS=reoccurance-free survival; SSIGN=stage, size, grade and necrosis. Bold is used to highlight the statistically significant P-values.