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Inhibition of insulin-stimulated redistribution of GLUT4 in skeletal muscle fibers by conditional rac1 knockout. The χ2 value (A) and fold increase in ratio of GLUT4 closely associated with the plasma membrane (B) in rac1flox/flox (f/f) and m-rac1-KO (m-KO) mice (8–10 wk old) (see Supplemental Table 1) are shown as means ± se for 5 independent experiments. ***P < 0.001.
