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. 2014 Sep 26;46(9):e115. doi: 10.1038/emm.2014.59

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Copyright © 2014 KSBMB.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Effects of phospholipase C-γ1 (PLC-γ1) small interfering RNA (siRNA) and 1,4,5-trisphosphate receptor (IP₃R) siRNA on cocultured human umbilical artery smooth muscle cell (HUASMC) viability. (a) PLC-γ1 and (c) IP₃R expression was determined in HUASMCs following transfection with the indicated siRNAs. The data represent five samples per group. (b and d) The effects of (b) PLC-γ1 and (d) IP₃R siRNA on HUASMC viability. Data are presented as the mean±s.d. of at least five independent experiments. Significantly different from the *control (Ctr), ^†Lip2000 and ^‡scrambled siRNA groups, P<0.05.