Table 1. Belfast HAPO mother and offspring population characteristics.
| Cohort with genotype and sum of skinfolds data at birth and 2 years | Cohort with genotype and sum of skinfolds data at birth and 6 years | |
|---|---|---|
| Sample size | 293 | 350 |
| Gestational age at OGTT (week) | 29.1±1.2 | 29.0±1.2 |
| Age at OGTT (year) | 30.3±5.2 | 29.9±5.3 |
| BMI at OGTT (kg m−2) | 28.5±4.6 | 28.2±4.2 |
| MAP at OGTT (mm Hg) | 83.7±7.9 | 83.3±8.0 |
| Fasting plasma glucose (mg dl−1) | 83.3±6.5 | 83.1±6.1 |
| 1-h plasma glucose (mg dl−1) | 134.9±29.2 | 135.1±29.9 |
| 2-h plasma glucose (mg dl−1) | 109.7±22.1 | 109.3±22.3 |
| Gestational age at delivery (week) | 40.1±1.1 | 40.1±1.0 |
| Maternal smoking (%) | 59 (20.1%) | 88 (25.1%) |
| Male offspring (n, %) | 132 (45.1%) | 169 (48.3%) |
| Primiparous births (n, %) | 158 (53.9%) | 175 (50.0%) |
| Offspring birth weight (g) | 3455.1±505.1 | 3457.3±503.9 |
| Offspring birth length (cm) | 50.9±2.1 | 50.8±2.2 |
| Head circumference (cm) | 35.1±1.3 | 35.2±1.3 |
| Fat mass (%) | 12.1±3.5 | 12.1±3.5 |
| Sum of skinfolds at birth (mm)* | 12.7, 3.2 | 12.6, 3.1 |
| Sum of skinfolds at 2 years (mm)* | 25.4, 7.1 | |
| Sum of skinfolds at 6 years (mm)* | 22.5, 9.9 |
Abbreviations: BMI, body mass index; MAP, mean arterial blood pressure; OGTT, oral glucose tolerance.
±indicates standard error.
*
Medians and interquartile ranges are reported for sum of skinfolds measurements because of skewed distributions.