Table 1.
Differentially expressed mitochondrial protein* between OVCAR8 and NCI_ADR/RES cells quantified by SILAC.
| Accession | Gene name | Protein name | SILAC ratio (NCI_ADR/RES/OVCAR8) |
|---|---|---|---|
| P08183 | MDR1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 24.16±5.56 |
| Q9BZF9 | UACA | Uvealautoantigen with coiled-coil domains and ankyrin repeats | 2.46±0.72 |
| Q9UQ90 | SPG7 | Spastic paraplegia 7 protein | 2.18±0.37 |
| Q9BX68 | HINT2 | Histidine triad nucleotide-binding protein 2, mitochondrial | 2.04±0.26 |
| P30536 | MBR | Mitochondrial benzodiazepine receptor | 2.41±0.60 |
| Q13232 | NME3 | Nucleoside diphosphate kinase 3 | 2.17±0.06 |
| P30048 | PRDX3 | Thioredoxin-dependent peroxide reductase, mitochondrial | 0.50±0.04 |
| P19367 | HK1 | Hexokinase-1 | 0.42±0.02 |
| Q969M1 | TOMM40B | Mitochondrial import receptor subunit TOM40B | 2.89±1.05 |
| Q6NUK1 | SCAMC1 | Mitochondrial ATP-Mg/Pi carrier protein 1 | 0.42±0.01 |
| E7FJF3 | GDAP1 | Ganglioside-induced differentiation-associated protein 1 | 2.55±0.89 |
| Q8N4T8 | CBR4 | Quinone reductase CBR4 | 2.51±0.05 |
| Q969P6 | TOP1MT | DNA topoisomerase I, mitochondrial | 2.32±0.36 |
| P13051 | UNG | Uracil-DNA glycosylase | 2.06±0.63 |
| Q9UHN1 | MTPOLB | DNA polymerase subunit gamma-2, mitochondrial | 2.00±0.53 |
| P55809 | OXCT1 | Succinyl-CoA:3-ketoacid-coenzyme A transferase 1 | 0.48±0.04 |
| Q5ST30 | VARS2 | Valyl-tRNAsynthetase, mitochondrial | 2.50±0.60 |
| Q9HA77 | CARS2 | Probable cysteinyl-tRNAsynthetase, mitochondrial | 0.30±0.03 |
| Q9UIJ7 | AK3 | GTP:AMP phosphotransferase mitochondrial | 2.58±0.22 |
| Q9Y6E7 | SIRT4 | NAD-dependent ADP-ribosyltransferase sirtuin-4 | 2.87±0.08 |
| O00746 | NME4 | Nucleoside diphosphate kinase, mitochondrial | 2.19±0.24 |
| Q9UDR5 | AASS | Alpha-aminoadipicsemialdehyde synthase, mitochondrial | 2.53±0.47 |
| P36957 | DLST | 2-oxoglutarate dehydrogenase complex component E2 | 2.48±1.20 |
| O14874 | BCKDK | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.47±1.34 |
| P49419 | ALDH6A1 | Aldehyde dehydrogenase family 6 member A1 | 2.13±0.27 |
| Q9UKU7 | ACAD8 | Isobutyryl-CoA dehydrogenase, mitochondrial | 2.04±0.26 |
| Q96H96 | COQ2 | Para-hydroxybenzoate--polyprenyltransferase, mitochondrial | 2.08±1.05 |
| Q8NE62 | CHDH | Choline dehydrogenase, mitochondrial | 2.99±0.30 |
| O94925 | GLS | Glutaminase kidney isoform, mitochondrial | 2.02±0.13 |
| P30837 | ALDH1B1 | Aldehyde dehydrogenase X, mitochondrial | 2.17±0.16 |
| Q9NUB1 | ACAS2L | Acetyl-CoA synthetase 2 | 2.05±0.94 |
| P45954 | ACADSB | Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial | 0.40±0.06 |
| Q9P2J9 | PDP2 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial | 0.44±0.04 |
| Q8IW45 | CARKD | Carbohydrate kinase domain-containing protein | 0.47±0.13 |
| A3KMH1 | VWA8 | von Willebrand factor A domain-containing protein 8 | 0.45±0.05 |
| Q13423 | NNT | NAD(P) transhydrogenase, mitochondrial | 0.49±0.02 |
| Q13825 | AUH | Methylglutaconyl-CoA hydratase, mitochondrial | 0.19±0.06 |
| P05166 | PCCB | Propionyl-CoA carboxylase beta chain, mitochondrial | 0.43±0.07 |
| P05165 | PCCA | Propionyl-CoA carboxylase alpha chain, mitochondrial | 0.42±0.06 |
| P28288 | ABCD3 | ATP-binding cassette sub-family D member 3 | 0.40±0.03 |
| Q305V2 | ND2 | NADH-ubiquinone oxidoreductase chain 2 | 2.17±1.23 |
| P13498 | CYBA | Cytochrome b(558) alpha chain | 2.07±1.46 |
| A7UNU5 | ETFDH | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 2.05±0.18 |
| E5KRX5 | SURF1 | Surfeit locus protein 1 | 2.44±0.77 |
| Q5TC12 | ATP11 | ATP synthase mitochondrial F1 complex assembly factor 1 | 0.36±0.01 |
| Q9NX18 | SDH5 | Succinate dehydrogenase assembly factor 2, mitochondrial | 0.28±0.07 |
| P21980 | TGM2 | Protein-glutamine gamma-glutamyltransferase 2 | 2.51±0.55 |
| P17931 | LGALS3 | Galactose-specific lectin 3 | 2.26±0.33 |
| Q96NE9 | FRMD6 | FERM domain-containing protein 6 | 2.32±0.16 |
| Q86UT6 | NLRX1 | NLR family member X1 | 4.02±0.16 |
| Q96CU9 | FOXRED1 | FAD-dependent oxidoreductase domain-containing protein 1 | 2.83±0.56 |
| Q3MIX3 | ADCK5 | Uncharacterized aarF domain-containing protein kinase 5 | 2.80±0.46 |
| Q53H82 | LACTB2 | Beta-lactamase-like protein 2 | 2.20±0.16 |
| Q9GZT6 | MDS025 | Coiled-coil domain-containing protein 90B, mitochondrial | 2.07±0.38 |
* Protein was annotated in Uniprot database as mitochondrial protein or to be located in mitochondria.