Figure 2.

A, Plasma glucose during hyperglycemic clamps was “clamped” similarly during the study by standardized infusion of glucose, in order to measure glucose-stimulated insulin secretion. B, Plasma insulin increased in response to hyperglycemia, and this response was diminished during the low-sodium (LS, red triangle) compared to high-sodium (HS, black circle) diet. C, C-peptide concentrations paralleled those of insulin.