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. Author manuscript; available in PMC: 2014 Oct 3.
Published in final edited form as: J Surg Res. 2013 Jan 1;184(2):730–738. doi: 10.1016/j.jss.2012.12.009

Figure 3. Simulated bacterial binding patterns to host epithelial cells are qualitatively similar to in-vitro results.

Figure 3

GFP-labeled MPAO-1 strain P. aeruginosa bacteria (green) were incubated with wounded monolayers of IEC-18 intestinal epithelial cells (blue), either previously irradiated or not. Bacteria bind primarily to the wound edge in non-irradiated monolayers, and more diffusely in irradiated conditions. Simulations in the ABM yielded qualitatively similar results using the hypothetical mechanism of host-bacterial interactions outlined in Figure 1.